Last-2-Weeks Endocrinology Strategy (MRCP Part 1)
- Crack Medicine

- Oct 20
- 3 min read
TL;DR
Your last-2-weeks strategy for Endocrinology (MRCP Part 1) should focus on consolidation, not expansion. Concentrate on Diabetes, Thyroid, Adrenal, Pituitary, and Calcium-Bone topics. Do daily question-based reviews, timed mocks, and pattern recognition. Use Crack Medicine’s QBank, lectures, and mocks to sharpen recall and eliminate errors.
Why this matters
Endocrinology contributes a reliable 10–15 % of the MRCP Part 1 exam and often overlaps with Cardiology, Nephrology, and Metabolism. In these final two weeks, your aim is efficiency — practising exam-style stems, revising hormonal axes, and mastering biochemical patterns.
Crack Medicine’s adaptive tools (QBank, mock analytics, and short lectures) are structured exactly for this sprint phase — helping you review high-yield material while maintaining confidence.
Five High-Yield Focus Areas
Diabetes Mellitus (Types 1 & 2) — diagnostic criteria, insulin regimens, DKA vs HHS, microvascular complications.
Thyroid Disorders — hypo/hyperthyroidism, amiodarone effects, postpartum thyroiditis, radioactive uptake findings.
Adrenal Axis — Addison’s, Cushing’s, Conn’s, cortisol interpretation, ACTH stimulation test.
Pituitary Lesions — acromegaly, prolactinoma, hypopituitarism, SIADH vs diabetes insipidus.
Calcium–Bone–MEN Syndromes — hyperparathyroidism, vitamin D deficiency, Paget’s disease, MEN 1/2A/2B.
These domains frequently appear as integrated case questions. Recognising lab patterns (e.g. “high cortisol + low ACTH = adrenal cause”) often yields easy marks.
Ten-Day Consolidation Plan
Day | Theme | Key Tasks |
1–2 | Diabetes | Review diagnostic thresholds, insulin types, complications; practise 80 MCQs. |
3–4 | Thyroid | Re-do TFT interpretation tables; 1 timed mock + 60 MCQs. |
5–6 | Adrenal & Pituitary | Revise hormonal feedback loops; memorise Cushing/Addison differentiators. |
7–8 | Calcium & Bone | Flashcards + question drills; review MEN diagrams. |
9 | Full Mock | Attempt under timed conditions; analyse errors. |
10 | Mixed Review | Revisit top 100 marked questions and endocrine images. |
Pro tip: avoid new PDFs or lecture slides. Focus purely on your own annotations — the brain recalls familiar formatting faster.

Mini-Case Example
Scenario: A 30-year-old woman complains of fatigue, weight gain, and constipation. TFTs:TSH = 18 mU/L, Free T4 = 6 pmol/L, Anti-TPO = positive.
Diagnosis: Primary hypothyroidism (Hashimoto’s thyroiditis).
Exam logic: Raised TSH + low T4 = primary failure; anti-TPO confirms autoimmune cause. Tip: In MRCP Part 1, if antibodies are mentioned, assume Hashimoto’s unless otherwise specified.
Five Common Pitfalls
Starting new topics instead of reinforcing weak ones.
Ignoring mixed-system questions where endocrine patterns hide in renal or cardiac cases.
Skipping mock reviews — learning happens in analysis, not attempts.
Confusing adrenal axis results (e.g., random vs morning cortisol).
Overlooking drug effects — steroids, lithium, and amiodarone twist lab values.
Rapid Study-Tip Checklist
✅ Spend 60 % of your day on question review, not fresh reading.
✅ Practise 45–50 timed MCQs daily (via Free MRCP MCQs).
✅ Summarise hormone axes using one-page diagrams.
✅ Re-attempt missed mocks via Start a mock test.
✅ Rewatch short endocrine lectures for quick recall boosts (see Crack Medicine Lectures).
✅ Sleep ≥ 7 hours — recall plummets under fatigue.
Frequent Traps in the Exam
Trap | Correction |
Treating every hypercalcaemia as parathyroid | Check PTH-independent causes (malignancy). |
Mixing SIADH vs cerebral salt wasting | Assess extracellular volume. |
Confusing insulin regimens | Know basal-bolus indications. |
Forgetting cortisol timing | Use 9 am samples; random levels mislead. |
Overlooking MEN patterns | Remember: MEN 1 = Pit-Pan-Para; MEN 2A = Med-Pheo-Para. |
FAQs
1. How many Endocrinology questions are in MRCP Part 1?
Around 15–20 directly endocrine, but up to 30 including cross-system questions.
2. Should I study new material now?
No — consolidate and rehearse. New notes rarely translate to retained knowledge.
3. How many full mocks should I sit?
Two in the final fortnight, ideally spaced 4–5 days apart.
4. What’s the most efficient review method?
Timed practice + targeted error analysis using Crack Medicine’s QBank analytics.
5. Are image-based endocrine questions common?
Yes — especially adrenal imaging, diabetic retinopathy, and thyroid scintigraphy patterns.
Ready to start?
Your final two weeks should be sharp, structured, and confident. Visit the MRCP Part 1 overview to align your schedule, attempt Free MRCP MCQs daily, and finish with a mock test to confirm readiness. Crack Medicine’s clinician-led resources are built for this final sprint.
Sources
MRCP(UK) — Part 1 Exam Format
National Institute for Health and Care Excellence (NICE): Endocrine and metabolic guidance



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